Red Cabernet reduces Risk of Alzheimer's

A new study directed by Mount Sinai School of Medicine in the US has found that moderate red wine consumption in a form of Cabernet Sauvignon may help reduce the incidence of Alzheimer's Disease (AD). Entitled "Moderate Consumption of Cabernet Sauvignon Attenuates ?-amyloid Neuropathology in a Mouse Model of Alzheimer's Disease" the breakthrough Study  is in press, and will be published in the November 2006 issue of The FASEB Journal, reports It  will also be presented at the "Society for Neuroscience Meeting"  in Atlanta , Georgia , October 14-18, 2006 .

"Our study is the first to report that moderate consumption of red wine in a form of Cabernet Sauvignon delivered in the drinking water for about 7 months significantly reduces AD-type ?-amyloid neuropathology, and memory deterioration in appx. 11-month-old transgenic mice that model Alzheimer's Disease," report researchers Dr. Giulio Maria Pasinetti and Dr. Jun Wang at Mount Sinai . "This study supports epidemiological evidence indicating that moderate wine consumption, within the range recommended by the FDA dietary guidelines of one drink per day for women and two for men, may help reduce the relative risk for Alzheimer's Disease clinical dementia."

"This new breakthrough is another step forward in Alzheimer's research at Mount Sinai and across the globe for this growing health concern that has devastating effects," say Giulio Maria Pasinetti, M.D., Ph.D., Professor of Psychiatry and Neuroscience, Director of the Neuro- inflammation Research Center at Mount Sinai School of Medicine and lead author of the study and Dr. Jun Wang, Assistant Professor of Psychiatry and co-Author of the study. "These findings give researchers and millions of families a glimpse of light at the end of the long dark tunnel for future prevention of this disease."

People with Alzheimer's disease exhibit elevated levels of beta-amyloid peptides that cause plaque buildup in the brain, which is the main characteristic of Alzheimer's disease. Presently, there are no known cures or effective preventive measures. While genetic factors are responsible in early-onset cases, they appear to play less of a role in late-onset or sporadic AD cases, the most common form of AD. However, lifestyle factors such as diet and now moderate wine consumption are receiving increasing attention for its potential preventative impact on Alzheimer's Disease.

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We had posted an Article on wine and health on June 16, 2002 which briefly affirmed the current findings. The study purports to give a scientific stamp of approval. Read:

Subhash Arora

September 19, 2006





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